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Dr. Richard H. Mann
Doctor of Podiatric Medicine
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Clinical Updates**

  • A Common-Sense Approach for the Nutritional Treatment of Peripheral Neuropathy 
    By Dr. Mann
    Blog, Clinical Update, Uncategorized
    March 4, 2022
    One in ten Americans, approximately 35 million people, have peripheral neuropathy (PN).  This is an epidemic by any definition.  Over the past decades the incidence of PN has grown dramatically as it [CLICK TO READ MORE]
  • Alcohol Consumption and Diabetic Peripheral Neuropathy
    By Dr. Mann
    Blog, Clinical Update, Uncategorized
    December 4, 2021
    A recently published paper in the journal Diabetes Therapy, examines the impact of alcohol use in diabetic patients with distal symmetrical polyneuropathy (DSP).  In the [CLICK TO READ MORE]
  • Benfotiamine and Alpha Lipoic Acid: Maximizing their Benefits
    By Dr. Mann
    Blog, Clinical Update
    December 3, 2021
    Summary: Benfotiamine and alpha lipoic acid (ALA) are two of the most commonly used nutrients in the treatment of peripheral neuropathy.  Although both may be beneficial, ALA is associated [CLICK TO READ MORE]
  • Treating Polyneuropathy by Improving Mitochondrial Function: Combining Light Therapy and Benfotiamine
    By Dr. Mann
    Blog, Clinical Update
    October 3, 2021
    In order for neurons to successfully perform their primary function of conducting action potentials, their mitochondria produce significantly greater amounts of energy, in the form of ATP, than all [CLICK TO READ MORE]
  • Peripheral Neuropathy in Type 2 Diabetes More Pernicious than Previously Thought
    By Dr. Mann
    Blog, Clinical Update
    July 27, 2021
    Summary: Recent studies indicate that type 2 diabetics with peripheral neuropathy are at increased risk of undergoing cognitive decline and earlier mortality than type 2 diabetics who do not have [CLICK TO READ MORE]
  • The High Prevalence of Peripheral Neuropathy in Patients with Prediabetes
    By Dr. Mann
    Blog, Clinical Update
    May 24, 2021
      A group of investigators from the UK recently performed an extensive review of the scientific literature in an attempt to better determine the prevalence of peripheral neuropathy in patients [CLICK TO READ MORE]
  • Peripheral Neuropathy and Mortality
    By Dr. Mann
    Blog, Clinical Update
    March 16, 2021
      Summary: In a ground-breaking study, investigators found that decreased sensation in the foot may be an underrecognized risk factor for death.  Mortality among adults with nondiabetic [CLICK TO READ MORE]
  • Update: Benfotiamine and Alzheimer’s Disease
    By Dr. Mann
    Blog, Clinical Update
    March 16, 2021
    This phase II multi-institutional study was the largest to date to look at the therapeutic benefits of using benfotiamine in patients suffering from AZ.  It followed, over a 12-month period, a cohort [CLICK TO READ MORE]
  • Peripheral Neuropathy and Sleep Apnea
    By Dr. Mann
    Blog, Clinical Update
    March 16, 2021
    Summary:  Obstructive sleep apnea (OSA) is a common, independent, and often-overlooked cause of peripheral neuropathy.  Additionally, in type 2 diabetics, OSA has been shown to significantly increase [CLICK TO READ MORE]
  • COVID-19 and Guillain–Barré Syndrome
    By Dr. Mann
    Blog, Clinical Update
    May 4, 2020
    On April 17, 2020, the online New England Journal of Medicine published the correspondence Guillain-Barré Syndrome Associated with SARS-CoV-2.  The paper was authored by a team of Italian physicians [CLICK TO READ MORE]
  • COVID-19 and Peripheral Neuropathy
    By Dr. Mann
    Blog, Clinical Update
    March 24, 2020
    At present, there is no reason to believe that COVID-19 is responsible for any sensory defects of the lower extremity.  In fact, The Foundation for Peripheral Neuropathy, a reputable patient advocacy [CLICK TO READ MORE]
  • Polyneuropathy
    By Dr. Mann
    Blog, Clinical Update
    December 10, 2019
    Polyneuropathy, the most common form of peripheral neuropathy, is a condition in which neurons of the peripheral nervous system dysfunction progressively, over time, in a length dependent manner-the [CLICK TO READ MORE]
  • Diabetic Polyneuropathy and Benfotiamine
    By Dr. Mann
    Blog, Clinical Update
    September 27, 2019
    During episodes of hyperglycemia, unlike most other cell types, the neurons and Schwann cells of the peripheral nervous system are unable to successfully prevent the rise of their internal glucose [CLICK TO READ MORE]
  • Prediabetic Neuropathy: Diagnosis and Treatment.
    By Dr. Mann
    Blog, Clinical Update
    August 21, 2019
    With estimates of the incidence of prediabetes in the USA at over 84 million people, prediabetes is an epidemic by any definition.  It is also one of the leading causes of peripheral neuropathy with [CLICK TO READ MORE]
  • Prediabetes and Peripheral Neuropathy
    By Dr. Mann
    Blog, Clinical Update
    July 25, 2019
    Summary: The association between peripheral neuropathy and prediabetes, although not well known by clinicians, is well established in the scientific literature. It is estimated that up to 15 million [CLICK TO READ MORE]
  • On Treating Alcoholic Peripheral Neuropathy
    By Dr. Mann
    Blog, Clinical Update
    June 24, 2019
    In 2015, according to The National Institutes of Health (NIH), there were approximately 15 million alcoholics in the US-with estimates suggesting that up to 10 million of them suffered from painful [CLICK TO READ MORE]
  • Type 2 Diabetes, Foot Ulcers and Cognition
    By Dr. Mann
    Blog, Clinical Update
    May 21, 2019
    Summary:  Research group finds that type 2 diabetics with foot ulcers possess fewer cognitive resources than a matched group of type 2 diabetics without foot ulcers. There is a well-established [CLICK TO READ MORE]
  • Benfotiamine and Alzheimer’s Disease
    By Dr. Mann
    Blog, Clinical Update
    April 17, 2019
    If you are one of the thousands of physicians who use benfotiamine, a high potency lipid-soluble form of thiamine (vitamin B1), in the treatment of polyneuropathy, you are certainly aware of its [CLICK TO READ MORE]
  • Peripheral Neuropathy vs. Polyneuropathy
    By Dr. Mann
    Blog, Clinical Update
    April 4, 2019
    Dr. Richard H Mann, DABPS, ret Chief Scientific Officer & Founder, Realm Labs, Makers of Nutrients to Improve the Function of the Nerves in the Feet and Legs. Which one of the following [CLICK TO READ MORE]
  • Reversing Thiamine Deficiency in Diabetic Polyneuropathy, an Important Therapeutic Goal
    By Dr. Mann
    Blog, Clinical Update
    March 6, 2019
    Clinician Alert: Reversing Thiamine (Vitamin B1) Deficiency in the Treatment of Diabetic Polyneuropathy: An Important Therapeutic Goal by Dr. Richard H Mann, DABPS, ret Chief Scientific Officer & [CLICK TO READ MORE]
  • Benfotiamine Shown to Improve Symptoms of Peripheral Neuropathy and Cognitive Function in Alcoholics
    By Dr. Mann
    Blog, Clinical Update
    January 28, 2019
    Clinician Alert: Patients Successfully Treated with Benfotiamine for Alcoholic Polyneuropathy May Also Experience Improved Cognitive Function Thiamine (Vitamin B1) deficiency is a well-known and [CLICK TO READ MORE]
  • Is Prediabetes a Risk Factor for Neuropathy?
    By Dr. Mann
    Blog, Clinical Update
    January 7, 2019
    Is Prediabetes a Risk Factor for Neuropathy? According to the American Diabetes Association, before people develop type 2 diabetes, they almost always have “prediabetes” – blood [CLICK TO READ MORE]

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